KEGG   Homo sapiens (human): 55361
Entry
55361             CDS       T01001                                 
Symbol
PI4K2A, NEDMSB, PI4KII, PIK42A
Name
(RefSeq) phosphatidylinositol 4-kinase type 2 alpha
  KO
K13711  phosphatidylinositol 4-kinase type 2 [EC:2.7.1.67]
Organism
hsa  Homo sapiens (human)
Pathway
hsa00562  Inositol phosphate metabolism
hsa01100  Metabolic pathways
hsa04070  Phosphatidylinositol signaling system
Module
hsa_M00130  Inositol phosphate metabolism, PI=> PIP2 => Ins(1,4,5)P3 => Ins(1,3,4,5)P4
Disease
H02470  Neurodevelopmental disorder with structural brain abnormalities
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09100 Metabolism
  09101 Carbohydrate metabolism
   00562 Inositol phosphate metabolism
    55361 (PI4K2A)
 09130 Environmental Information Processing
  09132 Signal transduction
   04070 Phosphatidylinositol signaling system
    55361 (PI4K2A)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   04131 Membrane trafficking [BR:hsa04131]
    55361 (PI4K2A)
Enzymes [BR:hsa01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.1  Phosphotransferases with an alcohol group as acceptor
    2.7.1.67  1-phosphatidylinositol 4-kinase
     55361 (PI4K2A)
Membrane trafficking [BR:hsa04131]
 Others
  Actin-binding proteins
   Nucleation-promoting factors (NPFs)
    55361 (PI4K2A)
SSDB
Motif
Pfam: PI3_PI4_kinase
Other DBs
NCBI-GeneID: 55361
NCBI-ProteinID: NP_060895
OMIM: 609763
HGNC: 30031
Ensembl: ENSG00000155252
UniProt: Q9BTU6
Structure
Position
10:97640671..97676434
AA seq 479 aa
MDETSPLVSPERAQPPDYTFPSGSGAHFPQVPGGAVRVAAAAGSGPSPPGSPGHDRERQP
LLDRARGAAAQGQTQTVAAQAQALAAQAAAAAHAAQAHRERNEFPEDPEFEAVVRQAELA
IERCIFPERIYQGSSGSYFVKDPQGRIIAVFKPKNEEPYGHLNPKWTKWLQKLCCPCCFG
RDCLVLNQGYLSEAGASLVDQKLELNIVPRTKVVYLASETFNYSAIDRVKSRGKRLALEK
VPKVGQRFNRIGLPPKVGSFQLFVEGYKDADYWLRRFEAEPLPENTNRQLLLQFERLVVL
DYIIRNTDRGNDNWLIKYDCPMDSSSSRDTDWVVVKEPVIKVAAIDNGLAFPLKHPDSWR
AYPFYWAWLPQAKVPFSQEIKDLILPKISDPNFVKDLEEDLYELFKKDPGFDRGQFHKQI
AVMRGQILNLTQALKDNKSPLHLVQMPPVIVETARSHQRSSSESYTQSFQSRKPFFSWW
NT seq 1440 nt   +upstreamnt  +downstreamnt
atggacgagacgagcccactagtgtcccccgagcgggcccaacccccggactacaccttc
ccgtcgggctcgggcgctcactttccgcaggtgcccgggggcgcggtccgagtggcggcg
gcggccggctcgggcccctctccgccgggctcgccgggccacgaccgcgagcggcagcca
ctgttggatcgggcccggggcgcggcggcccagggccagacccaaaccgtggcggcgcag
gcccaggctctggccgctcaggccgcggcggcagcccacgccgctcaggcccaccgcgag
cggaacgagttcccggaggatcctgagttcgaggcggtggtgcggcaggccgagctggcc
atcgagcgctgcatctttcccgagcgcatctaccagggctccagcggaagctacttcgtc
aaggaccctcaggggaggatcattgctgtcttcaaacccaagaatgaagagccctatggg
catcttaatcctaagtggaccaagtggctgcagaagctgtgctgtccttgctgctttggc
cgtgactgccttgtccttaaccagggctatctctcagaagcaggggccagcctggtggac
caaaaactggaactcaacattgttccccgtacaaaggtagtatacctggccagtgagacc
ttcaactatagtgccattgaccgagtgaagtccaggggcaagcggcttgcactagagaaa
gtgccaaaagttggacagcggtttaaccgcatcgggctaccaccaaaggttggttcattc
cagctctttgttgaaggctacaaagatgcagactattggctgcggcgttttgaagcagaa
cctcttcctgagaacactaaccggcaactactgctccagtttgagcggttggtggtgctg
gattacatcatccgcaacactgatcgaggcaatgacaactggctgattaaatatgactgt
ccaatggatagttctagctctcgggacacagactgggtggtggtgaaggagcctgttatc
aaggtggctgccatagacaatgggctggccttcccactgaagcatcctgactcctggagg
gcatatcctttttactgggcctggttgccccaggcgaaagtcccattttctcaggagatc
aaagatctgatccttccaaagatatcggaccctaacttcgtcaaggacttggaagaggac
ctatatgaactcttcaagaaagatcctggtttcgacaggggccagttccataagcagatt
gctgtcatgcggggccagatcttaaatctgacccaggccttgaaagacaacaagagtccc
ctgcacctcgtccagatgccacctgtgattgtcgagacggcccgttcccaccagcggtct
tctagcgagtcctacacacagagctttcagagccggaagcccttcttttcatggtggtag

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Ontology (3)   
   KEGG BRITE (3)   
Pathway (4)   
   KEGG PATHWAY (3)   
   KEGG MODULE (1)   
Disease (3)   
   KEGG DISEASE (1)   
   OMIM (2)   
Chemical substance (4)   
   KEGG COMPOUND (4)   
Chemical reaction (2)   
   KEGG ENZYME (1)   
   KEGG REACTION (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (18)   
   KEGG ORTHOLOGY (1)   
   RefGene (3)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   HGNC (1)   
   Ensembl (1)   
   RIKEN BRC-DNA (9)   
   OC (1)   
Protein sequence (3)   
   UniProt (1)   
   SWISS-PROT (1)   
   RefSeq(pep) (1)   
DNA sequence (17)   
   RefSeq(nuc) (1)   
   GenBank (8)   
   EMBL (8)   
3D Structure (6)   
   PDB (6)   
Protein domain (1)   
   Pfam (1)   
All databases (62)   

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